⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389016 | 0.83 | — | — | |
| SCHEMBL98446 | 0.75 | — | — | |
| SCHEMBL9560717 | 0.73 | CES1 (0.48) | — | |
| SCHEMBL6975600 | 0.71 | ALDH1A1 (0.43) | — | |
| SCHEMBL7059217 | 0.69 | TDP1 (0.32) | — | |
| SCHEMBL879224 | 0.67 | — | — | |
| SCHEMBL42538 | 0.67 | — | — | |
| SCHEMBL2517088 | 0.67 | — | — | |
| SCHEMBL1509717 | 0.67 | — | — | |
| SCHEMBL734443 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174151-B1 | THERAPEUTIC TREATMENT OF EOSINOPHILIA USING CHYMASE INHIBITORS AS THE ACTIVE INGREDIENT | DAIICHI ASUBIO PHARMA CO LTD (JP) | 2007-01-24 | — | — | EP | claimed |
| US-6677344-B2 | Chymase inhibitor for the treatment of eosinophilia | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2004-01-13 | — | — | US | claimed |
| US-6500835-B2 | FOR PROPHYLAXIS AND THERAPY OF FIBROSIS INVOLVING EXTRACELLULAR MATRIX DYSBOLISM HAVING A CHYMASE INHIBITOR AS AN EFFECTIVE INGREDIENT; SIDE EFFECT REDUCTION | SUNTORY LIMITED (JP) | 2002-12-31 | — | — | US | claimed |
| US-5393760-A | Cardiovascular disorders, antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | claimed |
| EP-0468231-B1 | Guanidins | HOFFMANN LA ROCHE (CH) | 1994-09-21 | — | — | EP | claimed |
| EP-0468231-A2 | Guanidins | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-29 | — | — | EP | claimed |
| EP-0107850-B1 | AMINOGLYCOSIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-06 | — | — | EP | claimed |
| US-4493831-A | ANTIBIOTICS, VIRICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-15 | — | — | US | claimed |
| EP-0107850-A1 | Aminoglycoside derivatives, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-05-09 | — | — | EP | claimed |
| US-20230146909-A1 | DYE INK COMPOSITION, BLACK DYE INK, INK JET RECORDING DYE INK, INK JET RECORDING METHOD, AND AQUEOUS DYE SOLUTION | FUJIFILM CORPORATION (JP) | 2023-05-11 | — | — | US | disclosed |
| US-9107953-B2 | Sustained release composition containing SDF-1 | ONO PHARMACEUTICAL CO., LTD. (JP) | 2015-08-18 | — | — | US | disclosed |
| US-20130243824-A1 | SUSTAINED RELEASE COMPOSITION CONTAINING SDF-1 | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-09-19 | — | — | US | disclosed |
| US-8435953-B2 | Sustained release composition containing SDF-1 | Tabata, Yasuhiko (JP) | 2013-05-07 | — | — | US | disclosed |
| EP-2218459-B1 | SUSTAINED RELEASE COMPOSITION CONTAINING SDF-1 | ONO PHARMACEUTICAL CO (JP) | 2012-02-01 | — | — | EP | disclosed |
| EP-0468231-A2 | Guanidins | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-29 | — | — | EP | disclosed |
| EP-0466125-A2 | Styryl compounds and their pharmaceutical use | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-5053494-A | FIBER REACTIVE POLYAZO DYE HAVING TWO VINYLSULFONE TYPE REACTIVE GROUPS THROUGH TRIAZINYL BRIDGING GROUP | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0266774-B1 | POLYAZO COMPOUND HAVING TWO VINYLSULFONE TYPE FIBER REACTIVE GROUPS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| EP-0316013-A2 | Silver halide photographic material having at least one dyed hydrophilic colloid layer | Fuji Photo Film Co., Ltd. (JP) | 1989-05-17 | — | — | EP | disclosed |
| EP-0266774-A1 | Polyazo compound having two vinylsulfone type fiber reactive groups | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-05-11 | — | — | EP | disclosed |