Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.59 |
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 8/20 | 0.48 |
| ▸ | CRHBP | P24387 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14041251 | 1.00 | MEN1 (0.59) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL4749194 | 1.00 | MEN1 (0.59) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL23607622 | 0.84 | METAP1 (0.58) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL23607623 | 0.84 | METAP1 (0.58) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL990867 | 0.81 | MEN1 (0.53) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL990866 | 0.81 | MEN1 (0.53) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL12950283 | 0.80 | MEN1 (0.52) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL10095181 | 0.76 | MEN1 (0.78) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL22559862 | 0.74 | KMT2A (1.00) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL29323764 | 0.74 | MEN1 (1.00) | MEN1KMT2AALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121861-A2 | PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-09 | — | — | WO | claimed |