Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 1.00 |
| ▸ | ESR1 | P03372 | 7/20 | 0.82 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.82 |
| ▸ | LMNA | P02545 | 4/20 | 0.82 |
| ▸ | MEN1 | O00255 | 3/20 | 0.82 |
| ▸ | MAPT | P10636 | 3/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.82 |
| ▸ | GAA | P10253 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.82 |
| ▸ | POLB | P06746 | 1/20 | 0.82 |
| ▸ | G6PD | P11413 | 1/20 | 0.82 |
| ▸ | PKM | P14618 | 1/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.82 |
| ▸ | RAB9A | P51151 | 1/20 | 0.82 |
| ▸ | DAB2IP | Q5VWQ8 | 1/20 | 0.82 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.82 |
| ▸ | SHBG | P04278 | 3/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542278 | 1.00 | CYP19A1 (1.00) | CYP19A1ESR1ESR2LMNAMEN1 | |
| SCHEMBL29565170 | 0.90 | ESR1 (1.00) | CYP19A1ESR1ESR2LMNAMEN1 | |
| SCHEMBL15491309 | 0.90 | ESR1 (1.00) | CYP19A1ESR1ESR2LMNAMEN1 | |
| SCHEMBL225052 | 0.90 | ESR1 (1.00) | CYP19A1ESR1ESR2LMNAMEN1 | |
| SCHEMBL6010005 | 0.90 | ESR1 (1.00) | CYP19A1ESR1ESR2LMNAMEN1 | |
| SCHEMBL13123058 | 0.90 | ESR1 (1.00) | CYP19A1ESR1ESR2LMNAMEN1 | |
| SCHEMBL225053 | 0.90 | ESR1 (1.00) | CYP19A1ESR1ESR2LMNAMEN1 | |
| SCHEMBL12027476 | 0.90 | ESR1 (1.00) | CYP19A1ESR1ESR2LMNAMEN1 | |
| SCHEMBL4206793 | 0.87 | CYP19A1 (1.00) | CYP19A1ESR1ESR2LMNAMEN1 | |
| SCHEMBL5025553 | 0.87 | CYP19A1 (1.00) | CYP19A1ESR1ESR2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014131891-A1 | USE OF FETUIN-B FOR CULTURE OF OOCYTES | Rheinisch-Westfälische Technische Hochschule Aachen (DE) | 2014-09-04 | — | — | WO | claimed |
| US-20040223983-A1 | Pharmaceutical preparations, use of these preparations and process for increasing the biovailability of pharmaceutical substances to be administered perorally | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-11-11 | — | — | US | claimed |
| WO-2014131891-A1 | USE OF FETUIN-B FOR CULTURE OF OOCYTES | Rheinisch-Westfälische Technische Hochschule Aachen (DE) | 2014-09-04 | — | — | WO | disclosed |
| WO-2008141318-A1 | DEVICE FOR DETERMINING RISK OF DEVELOPING BREAST CANCER AND METHOD THEREOF | DR. SUSAN LOVE RESEARCH FOUNDATION (US) | 2008-11-20 | — | — | WO | disclosed |
| US-20040223983-A1 | Pharmaceutical preparations, use of these preparations and process for increasing the biovailability of pharmaceutical substances to be administered perorally | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-11-11 | — | — | US | disclosed |
| US-4522758-A | Method of preparing 2-fluoro-17β-estradiol | ELI LILLY AND COMPANY (US) | 1985-06-11 | — | — | US | disclosed |