Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749411 | 1.00 | KDM2B (0.33) | KDM2BMEN1KMT2AKDRSLC2A1 | |
| SCHEMBL4748997 | 0.91 | MEN1 (0.34) | KDM2BMEN1KMT2AESR1MGLL | |
| SCHEMBL4028191 | 0.91 | KIF11 (0.35) | KDM2BMEN1KMT2AESR1MGLL | |
| SCHEMBL4749199 | 0.91 | MEN1 (0.34) | KDM2BMEN1KMT2AESR1MGLL | |
| SCHEMBL4024525 | 0.90 | MEN1 (0.35) | KDM2BMEN1KMT2ASLC2A1SLC2A4 | |
| SCHEMBL4024540 | 0.90 | MEN1 (0.35) | KDM2BMEN1KMT2ASLC2A1SLC2A4 | |
| SCHEMBL13720775 | 0.90 | MEN1 (0.35) | KDM2BMEN1KMT2ASLC2A1SLC2A4 | |
| SCHEMBL4749122 | 0.90 | KDR (0.35) | KDM2BMEN1KMT2AKDRMGLL | |
| SCHEMBL4029040 | 0.90 | DRD3 (0.35) | KDM2BMEN1KMT2AESR1 | |
| SCHEMBL4026512 | 0.90 | NPC1 (0.41) | KDM2BMEN1KMT2AKDRSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |