Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | TACR2 | P21452 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854089 | 1.00 | KCNH2 (0.51) | KCNH2HTR2ACSNK1ESIGMAR1CETP | |
| SCHEMBL7062802 | 0.98 | SIGMAR1 (0.49) | KCNH2HTR2ACSNK1ESIGMAR1CETP | |
| SCHEMBL2790330 | 0.93 | KCNH2 (0.46) | KCNH2HTR2ASIGMAR1ADRA2ASLC6A2 | |
| SCHEMBL11785905 | 0.89 | SIGMAR1 (0.50) | KCNH2HTR2ASIGMAR1 | |
| SCHEMBL18093956 | 0.89 | SIGMAR1 (0.49) | KCNH2SIGMAR1ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL3322171 | 0.84 | KCNH2 (0.53) | KCNH2HTR2ACSNK1ESIGMAR1CETP | |
| SCHEMBL11785493 | 0.84 | SIGMAR1 (0.47) | KCNH2SIGMAR1 | |
| SCHEMBL28523845 | 0.84 | CSNK1E (0.57) | CSNK1ETP53CNR2 | |
| SCHEMBL27952343 | 0.84 | KCNH2 (0.53) | KCNH2HTR2ACSNK1ESIGMAR1CETP | |
| SCHEMBL27984757 | 0.84 | KCNH2 (0.53) | KCNH2HTR2ACSNK1ESIGMAR1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008120839-A1 | NOVEL ORGANIC SEMICONDUCTOR COMPOUND, AND ORGANIC THIN FILM TRANSISTOR USING THE SAME | GYEONGSANG NATIONAL UNIVERSITY INDUSTRIAL AND ACADEMIC COLLABORATION FOUNDATION (KR) | 2008-10-09 | — | — | WO | disclosed |
| EP-1028944-B1 | FLUORINATED NAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2006-01-11 | — | — | EP | disclosed |
| US-6491989-B1 | 6,7-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES, 1,1,6,7-TETRAFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES, 1,6,7-TRIFLUORONAPHTHALENE DERIVATIVES AND 2,3-DIFLUORONAPHTHALENE DERIVATIVES | AVENTIS RESEACH & TECHNOLOGIES GMBH & CO. KG (DE) | 2002-12-10 | — | — | US | disclosed |
| EP-1028944-A1 | FLUORINATED NAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | Aventis Research & Technologies GmbH & Co. KG (DE) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999023074-A1 | FLUORINATED NAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-05-14 | — | — | WO | disclosed |