⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL474963 | 1.00 | — | — | |
| SCHEMBL7649349 | 0.78 | GRIK1 (0.35) | — | |
| SCHEMBL15467869 | 0.77 | — | — | |
| SCHEMBL9746694 | 0.77 | — | — | |
| SCHEMBL3840926 | 0.77 | ABCC4 (0.34) | — | |
| SCHEMBL3638948 | 0.76 | — | — | |
| SCHEMBL28365989 | 0.75 | — | — | |
| SCHEMBL31636 | 0.75 | GRIK1 (0.48) | — | |
| SCHEMBL8051141 | 0.74 | — | — | |
| SCHEMBL11483449 | 0.74 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348696-B1 | Use of optically active clausenamides for the preparation of pharmaceutical compositions, pharmaceutical compositions containing the same | INST MATERIA MEDICA CAMS (CN) | 2012-02-01 | — | — | EP | disclosed |