Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.58 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 14/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749680 | 1.00 | PARP1 (0.58) | PARP1GSTO1KCNQ1LMNAMAPT | |
| SCHEMBL4749684 | 1.00 | PARP1 (0.58) | PARP1GSTO1KCNQ1LMNAMAPT | |
| SCHEMBL4747516 | 0.88 | PARP1 (0.56) | PARP1GSTO1KCNQ1LMNAMAPT | |
| SCHEMBL4747513 | 0.88 | PARP1 (0.56) | PARP1GSTO1KCNQ1LMNAMAPT | |
| SCHEMBL4747519 | 0.88 | PARP1 (0.56) | PARP1GSTO1KCNQ1LMNAMAPT | |
| SCHEMBL4749660 | 0.86 | PARP1 (0.54) | PARP1GSTO1KCNQ1LMNAMAPT | |
| SCHEMBL4749658 | 0.86 | PARP1 (0.54) | PARP1GSTO1KCNQ1LMNAMAPT | |
| SCHEMBL4750846 | 0.85 | RAB9A (0.70) | PARP1GSTO1KCNQ1LMNAMAPT | |
| SCHEMBL4750855 | 0.85 | RAB9A (0.70) | PARP1GSTO1KCNQ1LMNAMAPT | |
| SCHEMBL4750849 | 0.85 | RAB9A (0.70) | PARP1GSTO1KCNQ1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | claimed |