Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308721 | 0.75 | — | — | |
| SCHEMBL18191087 | 0.67 | TSHR (0.59) | TSHRALDH1A1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL9247626 | 0.66 | SMN1; SMN2 (0.35) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL31085615 | 0.65 | TSHR (0.39) | TSHRALDH1A1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL5134911 | 0.65 | TSHR (0.39) | TSHRALDH1A1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL3741955 | 0.63 | — | — | |
| SCHEMBL8675509 | 0.63 | TSHR (0.54) | TSHRALDH1A1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL44701 | 0.63 | — | — | |
| SCHEMBL15786341 | 0.63 | — | — | |
| SCHEMBL1144232 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008138363-A1 | NITROGEN-CONTAINING POLYETHER-POLYSILOXANE BLOCK COPOLYMERS, PROCESS FOR PREPARING THEM AND THEIR USE FOR ENHANCING THE SURFACE PROPERTIES OF FABRICS AND FIBRES | EVONIK GOLDSCHMIDT GMBH (DE) | 2008-11-20 | — | — | WO | claimed |
| JP-59172571-A | — | — | None | — | — | JP | disclosed |
| WO-2008138363-A1 | NITROGEN-CONTAINING POLYETHER-POLYSILOXANE BLOCK COPOLYMERS, PROCESS FOR PREPARING THEM AND THEIR USE FOR ENHANCING THE SURFACE PROPERTIES OF FABRICS AND FIBRES | EVONIK GOLDSCHMIDT GMBH (DE) | 2008-11-20 | — | — | WO | disclosed |
| JP-S59172571-A | ELECTRICALLY CONDUCTIVE ADHESIVE | HITACHI CHEM CO LTD | 1984-09-29 | — | — | JP | disclosed |