Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289461 | 0.86 | EBP (0.40) | MAPTKMT2ACA1CA2CA4 | |
| SCHEMBL4291328 | 0.86 | CA1 (0.38) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL4290915 | 0.84 | KMT2A (0.41) | MAPTHTTKMT2AMEN1GAA | |
| SCHEMBL4294740 | 0.84 | MAN1B1 (0.43) | RENCA1CA2CA4CA9 | |
| SCHEMBL4291053 | 0.83 | KDM4E (0.39) | MAPTKMT2AMEN1CA1CA2 | |
| SCHEMBL4281787 | 0.83 | MEN1 (0.41) | MAPTKMT2AMEN1GAA | |
| SCHEMBL4289734 | 0.82 | MAPT (0.43) | MAPTHTTKMT2AMEN1GAA | |
| SCHEMBL4289730 | 0.82 | MAPT (0.43) | MAPTHTTKMT2AMEN1GAA | |
| SCHEMBL4281693 | 0.80 | CCR3 (0.39) | KMT2AMEN1ADRB1GAA | |
| SCHEMBL4287399 | 0.79 | LTA4H (0.48) | MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |