Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.94 |
| ▸ | MAOB | P27338 | 4/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21063 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL3830237 | 0.94 | LOXL2 (0.94) | LOXL2MAOBTAAR1HRH3IDO1 | |
| Hydrochloric Acid SCHEMBL3847812 | 0.94 | LOXL2 (0.94) | LOXL2MAOBTAAR1HRH3IDO1 | |
| Iodide SCHEMBL20838270 | 0.94 | LOXL2 (0.94) | LOXL2MAOBTAAR1HRH3IDO1 | |
| Bromide SCHEMBL31513710 | 0.94 | LOXL2 (0.94) | LOXL2MAOBTAAR1HRH3IDO1 | |
| Hydrochloric Acid SCHEMBL6153650 | 0.92 | LOXL2 (0.89) | LOXL2MAOBTAAR1HRH3IDO1 | |
| Ethylamine SCHEMBL1568352 | 0.89 | LOXL2 (0.84) | LOXL2MAOBTAAR1HRH3IDO1 | |
| SCHEMBL14829415 | 0.89 | LOXL2 (0.84) | LOXL2MAOBTAAR1HRH3IDO1 | |
| SCHEMBL4415525 | 0.89 | LOXL2 (0.84) | LOXL2MAOBTAAR1HRH3IDO1 | |
| SCHEMBL28416503 | 0.87 | LOXL2 (0.80) | LOXL2MAOBTAAR1HRH3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119772-A1 | AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES | MEDIVIR AB (SE) | 2008-10-09 | — | — | WO | disclosed |
| US-4021567-A | FOR PSYCHOSOMATIC AND PSYCHOTIC DISTURBANCES | SYNTHELABO (FR) | 1977-05-03 | — | — | US | disclosed |