Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12668094 | 0.78 | IKBKB (0.33) | IKBKB | |
| SCHEMBL3965341 | 0.75 | IKBKB (0.38) | IKBKB | |
| SCHEMBL21736983 | 0.64 | GRIN2D (0.34) | — | |
| SCHEMBL24250240 | 0.64 | SLC6A2 (0.41) | IKBKB | |
| SCHEMBL4689649 | 0.63 | TLR8 (0.49) | — | |
| SCHEMBL20038315 | 0.62 | SLC6A2 (0.43) | IKBKB | |
| SCHEMBL26955100 | 0.62 | PSMB5 (0.34) | — | |
| SCHEMBL9487271 | 0.62 | HMGCR (0.42) | — | |
| SCHEMBL3966501 | 0.61 | NOS3 (0.41) | IKBKB | |
| SCHEMBL19659219 | 0.60 | SLC6A2 (0.38) | IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879896-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006107784-A1 | IMIDAZOPYRIDAZINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-10-12 | — | — | WO | disclosed |