SCHEMBL475022

SCHEMBL475022

C=CCNC(=O)C(=CN)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 1/20 0.41
ALDH1A1 P00352 6/20 0.39
KMT2A Q03164 1/20 0.38
HPGD P15428 2/20 0.35
LMNA P02545 1/20 0.35
FAAH O00519 1/20 0.34
RAB9A P51151 2/20 0.34
KDM4E B2RXH2 3/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22851991 0.81 ALDH1A1 (0.41) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL4933353 0.78
SCHEMBL4952777 0.75 TSHR (0.56) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL9283338 0.73 TSHR (0.42) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL19063392 0.72 TSHR (0.45) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL2754316 0.72 TSHR (0.45) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL4440627 0.72
SCHEMBL29424 0.72
SCHEMBL9819713 0.70 TSHR (0.46) TSHRSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL9868758 0.70 ALDH1A1 (0.50) TSHRSMN1; SMN2MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2008506794-A 2008-03-06 JP claimed
EP-1771532-A1 USE OF GRAFT POLYMERS Rohmax Additives GmbH (DE) 2007-04-11 EP claimed
WO-2006007934-A1 USE OF GRAFT POLYMERS ROHMAX ADDITIVES GMBH (DE) 2006-01-26 WO claimed
EP-1608726-A1 LUBRICATING OIL COMPOSITION WITH GOOD FRICTIONAL PROPERTIES Rohmax Additives GmbH (DE) 2005-12-28 EP claimed
WO-2004087850-A1 LUBRICATING OIL COMPOSITION WITH GOOD FRICTIONAL PROPERTIES ROHMAX ADDITIVES GMBH (DE) 2004-10-14 WO claimed
EP-1753847-B1 LUBRICATING GREASE HAVING A HIGH WATER-RESISTANCE EVONIK OIL ADDITIVES GMBH (DE) 2018-05-23 EP disclosed
EP-2686352-B1 COPOLYMERS COMPRISING ESTER GROUPS AND USE THEREOF IN LUBRICANTS EVONIK OIL ADDITIVES GMBH (DE) 2018-04-04 EP disclosed
EP-2411426-B1 (METH)ACRYLATE POLYMERS AND THE USE THEREOF AS POLYMER-BOUND UV INITIATORS OR ADDITIVE TO UV-CURABLE RESINS EVONIK ROEHM GMBH (DE) 2016-08-17 EP disclosed
US-20140206823-A1 METHOD FOR REDUCING THE HALOGEN CONTENT OF A POLYMER EVONIK OIL ADDITIVES GMBH (DE) 2014-07-24 US disclosed
US-8785358-B2 Process for producing lubricating grease EVONIK ROHMAX ADDITIVES GMBH (DE) 2014-07-22 US disclosed
EP-2686352-A1 COPOLYMERS COMPRISING ESTER GROUPS AND USE THEREOF IN LUBRICANTS Evonik Oil Additives GmbH (DE) 2014-01-22 EP disclosed
EP-2411466-B1 COMPOSITION COMPRISING AS THE AQUEOUS DISPERSION PREFERABLY (METH)ACRYLATE POLYMERS CONTAINING BENZOPHENONE IN A MIXTURE WITH (METH)ACRYLATE POLYMERS DIFFERENT THEREFROM AND THE USE OF SAID COMPOSITION EVONIK ROEHM GMBH (DE) 2013-07-17 EP disclosed
WO-2006094520-A1 PROCESS FOR PRODUCING LUBRICATING GREASE ROHMAX ADDITIVES GMBH (DE) 2006-09-14 WO disclosed
WO-2006015751-A1 METHOD FOR RADICAL POLYMERIZATION OF ETHYLENICALLY UNSATURATED COMPOUNDS ROHMAX ADDITIVES GMBH (DE) 2006-02-16 WO disclosed
WO-2006007934-A1 USE OF GRAFT POLYMERS ROHMAX ADDITIVES GMBH (DE) 2006-01-26 WO disclosed
EP-1608726-A1 LUBRICATING OIL COMPOSITION WITH GOOD FRICTIONAL PROPERTIES Rohmax Additives GmbH (DE) 2005-12-28 EP disclosed
WO-2005108531-A2 USE OF POLYALKYL(METH)ACRYLATES IN LUBRICATING OIL COMPOSITIONS ROHMAX ADDITIVES GMBH (DE) 2005-11-17 WO disclosed
WO-2005108532-A1 LUBRICATING GREASE HAVING A HIGH WATER-RESISTANCE ROHMAX ADDITIVES GMBH (DE) 2005-11-17 WO disclosed
US-20050245406-A1 excellent consistency and great homogeneity; dispersion of thickener, lubricant, and structure improver is copolymer of a C6-C30 alkyl (meth)acrylate ROHMAX ADDITIVES GMBH (DE) 2005-11-03 US disclosed
WO-2004087850-A1 LUBRICATING OIL COMPOSITION WITH GOOD FRICTIONAL PROPERTIES ROHMAX ADDITIVES GMBH (DE) 2004-10-14 WO disclosed