Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950505 | 0.90 | PTGER4 (0.62) | PTGER4PTGER2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL10826146 | 0.87 | SLC2A1 (0.54) | PTGER4PTGER2MAPTMEN1KMT2A | |
| SCHEMBL30028779 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2AAPP | |
| SCHEMBL31040308 | 0.83 | NPC1 (0.52) | PTGER4PTGER2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL31040310 | 0.81 | KDM4E (0.54) | ALDH1A1MAPTHSD17B10KDM4CMEN1 | |
| SCHEMBL4704085 | 0.80 | FFAR4 (0.63) | PTGER4PTGER2MAPTNPC1RAB9A | |
| SCHEMBL31040288 | 0.80 | MEN1 (0.47) | ALDH1A1MAPTHSD17B10KDM4CMEN1 | |
| SCHEMBL31040315 | 0.80 | KDM4E (0.52) | ALDH1A1MAPTHSD17B10KDM4CMEN1 | |
| SCHEMBL31040282 | 0.80 | MEN1 (0.47) | ALDH1A1MAPTHSD17B10KDM4CMEN1 | |
| SCHEMBL4747314 | 0.79 | PPARA (0.45) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008128166-A1 | DEUTERATED DERIVATIVES OF 4-(6-FLUORO-1, 2-BENZISOXAZOL-3-YL) PIPERIDINE COMPOUNDS | CONCERT PHARMACEUTICALS INC. (US) | 2008-10-23 | — | — | WO | disclosed |