Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23247492 | 0.77 | HCRTR1 (0.31) | HCRTR1HCRTR2 | |
| SCHEMBL933804 | 0.75 | SSTR3 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL1914123 | 0.75 | KDM5A (0.31) | KDM5AKDM4C | |
| SCHEMBL17938125 | 0.73 | ALDH1A1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL17938124 | 0.73 | ALDH1A1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL1984447 | 0.72 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL1984448 | 0.72 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL1914368 | 0.72 | JAK3 (0.33) | KDM5AKDM4C | |
| SCHEMBL15848316 | 0.71 | SSTR3 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL15848318 | 0.71 | SSTR3 (0.39) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2410844-A1 | INHIBITORS OF HEPATITIS C VIRUS REPLICATION | Merck Sharp & Dohme Corp. (US) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010111483-A1 | INHIBITORS OF HEPATITIS C VIRUS REPLICATION | MERCK SHARP & DOHME CORP. (US) | 2010-09-30 | — | — | WO | disclosed |