Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 14/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787877 | 0.90 | CCKBR (0.74) | CCKBR | |
| SCHEMBL14041933 | 0.89 | CCKBR (0.77) | CCKBR | |
| SCHEMBL4747136 | 0.87 | CCKBR (0.80) | CCKBR | |
| SCHEMBL13146539 | 0.83 | CCKBR (0.63) | CCKBREPHX2KDM4EMAPT | |
| SCHEMBL13146627 | 0.82 | CCKBR (0.54) | CCKBREPHX2KDM4EKMT2AMAPT | |
| SCHEMBL3097887 | 0.80 | CCKBR (0.59) | CCKBRKDM4EMAPT | |
| SCHEMBL3745887 | 0.79 | GRIK1 (0.56) | CCKBR | |
| SCHEMBL15227852 | 0.78 | CCKBR (0.57) | CCKBR | |
| SCHEMBL1386421 | 0.77 | CCKBR (1.00) | CCKBR | |
| SCHEMBL13146586 | 0.77 | CCKBR (0.68) | CCKBREPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124524-A2 | ARYL SULFONAMIDE COMPOUNDS AS MODULATORS OF THE CCK2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-16 | — | — | WO | claimed |
| WO-2008124524-A2 | ARYL SULFONAMIDE COMPOUNDS AS MODULATORS OF THE CCK2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-16 | — | — | WO | disclosed |