⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204492 | 0.70 | — | — | |
| Methane Boronic Acid SCHEMBL935322 | 0.60 | — | — | |
| SCHEMBL732153 | 0.56 | — | — | |
| SCHEMBL1948103 | 0.56 | — | — | |
| Acetaldehyde SCHEMBL3945841 | 0.54 | — | — | |
| Acetaldehyde SCHEMBL1330497 | 0.54 | — | — | |
| Acetaldehyde SCHEMBL1331732 | 0.54 | — | — | |
| SCHEMBL6686462 | 0.54 | — | — | |
| Acetaldehyde SCHEMBL20411618 | 0.54 | — | — | |
| Acetaldehyde SCHEMBL2338299 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499631-B2 | Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity | IMMUNOMEDICS, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20160032004-A1 | Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-02-04 | — | — | US | disclosed |
| US-8999344-B2 | Immunoconjugates with an intracellularly-cleavable linkage | IMMUNOMEDICS, INC. (US) | 2015-04-07 | — | — | US | disclosed |
| US-20140328752-A1 | Immunoconjugates with an Intracellularly-Cleavable Linkage | IMMUNOMEDICS, INC. | 2014-11-06 | — | — | US | disclosed |
| WO-2008145733-A2 | NOVEL CHEMICAL COMPOUNDS, PRODUCTION THEREOF, AND USE THEREOF | UNIVERSITÄT LEIPZIG (DE) | 2008-12-04 | — | — | WO | disclosed |
| US-6696380-B2 | Procatalysts, catalyst systems, and use in olefin polymerization | WESTLAKE LONGVIEW CORPORATION | 2004-02-24 | — | — | US | disclosed |
| US-6677410-B2 | COORDINATION CATALYSTS | EASTMAN CHEMICAL COMPANY | 2004-01-13 | — | — | US | disclosed |
| US-20030004285-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | WESTLAKE LONGVIEW CORPORATION | 2003-01-02 | — | — | US | disclosed |
| US-6465383-B2 | COORDINATION CATALYST | EASTMAN CHEMICAL COMPANY | 2002-10-15 | — | — | US | disclosed |
| US-20010051587-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | WESTLAKE LONGVIEW CORPORATION | 2001-12-13 | — | — | US | disclosed |
| US-20010031841-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | WESTLAKE LONGVIEW CORPORATION | 2001-10-18 | — | — | US | disclosed |
| US-20010029286-A1 | Procatalysts, catalyst systems, and use in OLEFIN polymerization | EASTMAN CHEMICAL COMPANY, A CORP. OF DELAWARE | 2001-10-11 | — | — | US | disclosed |
| US-20010025005-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE | 2001-09-27 | — | — | US | disclosed |
| WO-2001051527-A1 | PROCATALYSTS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051526-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051528-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051529-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| EP-0376188-B1 | Process for producing a polyolefin | TOSOH CORP (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5162464-A | Catalyst of magnesium, titanium compound, organoaluminum compound, boron compound, aluminum halide, organic metal compound | TOSOH CORPORATION (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0376188-A2 | Process for producing a polyolefin | Tosoh Corporation (JP) | 1990-07-04 | — | — | EP | disclosed |