SCHEMBL732153

SCHEMBL732153

C=CB(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8966404 0.74
SCHEMBL18563466 0.70
SCHEMBL13492116 0.70
SCHEMBL20489374 0.62
SCHEMBL339914 0.59
SCHEMBL4750509 0.56
Propene SCHEMBL4864523 0.56
SCHEMBL2802183 0.56
SCHEMBL149881 0.56
Propene SCHEMBL4948068 0.54 TSHR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994003529-A1 HIGH CHAR YIELD SILAZANE DERIVED PRECERAMIC POLYMERS AND CURED COMPOSITIONS THEREOF THE B.F. GOODRICH COMPANY (US) 1994-02-17 WO claimed
US-5256487-A High char yield silazane derived preceramic polymers and cured compositions thereof THE B. F. GOODRICH COMPANY (US) 1993-10-26 US claimed
US-20180179175-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD PHARMASSET LLC 2018-06-28 US disclosed
US-9890134-B2 Processes for preparing antiviral compounds GILEAD PHARMASSET LLC (US) 2018-02-13 US disclosed
US-20170283390-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2017-10-05 US disclosed
US-9670187-B2 Processes for preparing antiviral compounds GILEAD PHARMASSET LLC (US) 2017-06-06 US disclosed
US-20150361073-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2015-12-17 US disclosed
US-8461201-B2 Trihydroxy polyunsaturated eicosanoid derivatives UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2013-06-11 US disclosed
US-8137990-B2 Compositions for chemiluminescent detection of hydrogen peroxide LUMIGEN, INC. (US) 2012-03-20 US disclosed
US-20110237545-A1 TRIHYDROXY POLYUNSATURATED EICOSANOID DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2011-09-29 US disclosed
US-20100267749-A1 TRISUBSTITUTED FUROPYRIMIDINES AND USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-10-21 US disclosed
EP-0680341-B1 PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS SONUS PHARMA INC (US) 2001-05-09 EP disclosed
EP-1038535-A2 Use of selected perfluorocarbons for the preparation of diagnostic ultrasound contrast agents SONUS PHARMACEUTICALS, INC. (US) 2000-09-27 EP disclosed
EP-0680341-A1 PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS SONUS PHARMACEUTICALS, INC. (US) 1995-11-08 EP disclosed
WO-1994016739-A1 PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS SONUS PHARMACEUTICALS, INC. (US) 1994-08-04 WO disclosed
WO-1994003529-A1 HIGH CHAR YIELD SILAZANE DERIVED PRECERAMIC POLYMERS AND CURED COMPOSITIONS THEREOF THE B.F. GOODRICH COMPANY (US) 1994-02-17 WO disclosed
US-5256487-A High char yield silazane derived preceramic polymers and cured compositions thereof THE B. F. GOODRICH COMPANY (US) 1993-10-26 US disclosed
US-4115492-A SPINNING, COOLING, DRAWING THE DOW CHEMICAL COMPANY (US) 1978-09-19 US disclosed
US-4020230-A Microporous polyethylene hollow fibers and process of preparing them THE DOW CHEMICAL COMPANY (US) 1977-04-26 US disclosed
US-3946131-A Glass fibers coated with silicon containing aminimide compounds OWENS-CORNING FIBERGLAS CORPORATION (US) 1976-03-23 US disclosed