SCHEMBL4750528

SCHEMBL4750528

C#CC(C)(C)NS(=O)(=O)N1CCOC1=O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.35
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18332195 0.74 PIK3CD (0.33) PIK3CD
SCHEMBL897720 0.73 KDM4E (0.36) PIK3CDKDM4E
SCHEMBL13158266 0.73 KDM4E (0.34) PIK3CDKDM4E
SCHEMBL6983526 0.72 PIK3CD (0.40) PIK3CDKDM4E
SCHEMBL19342028 0.71 KDM4E (0.33) PIK3CDKDM4E
SCHEMBL1146179 0.70 KDM4E (0.35) PIK3CDKDM4E
SCHEMBL22339126 0.70 PIK3CD (0.35) PIK3CDKDM4E
SCHEMBL21572190 0.70 PIK3CD (0.31) PIK3CD
SCHEMBL21572217 0.69 KDM4E (0.33) PIK3CDKDM4E
SCHEMBL23009276 0.69 PIK3CD (0.33) PIK3CDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008147763-A1 MMP INHIBITORS AND METHODS OF USE THEREOF ARRAY BIOPHARMA INC. (US) 2008-12-04 WO disclosed
WO-2008147764-A1 MMP INHIBITORS AND METHODS OF USE THEREOF ARRAY BIOPHARMA, INC. (US) 2008-12-04 WO disclosed