Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28171064 | 0.84 | PARG (0.33) | — | |
| SCHEMBL22528995 | 0.76 | KDM4E (0.33) | KDM4E | |
| SCHEMBL22290089 | 0.76 | NAAA (0.41) | — | |
| SCHEMBL897720 | 0.75 | KDM4E (0.36) | PIK3CDKDM4E | |
| SCHEMBL22339126 | 0.75 | PIK3CD (0.35) | PIK3CDKDM4E | |
| SCHEMBL12195850 | 0.75 | ALDH1A1 (0.36) | KDM4E | |
| SCHEMBL13158266 | 0.75 | KDM4E (0.34) | PIK3CDKDM4E | |
| SCHEMBL1220907 | 0.74 | GBA1 (0.36) | — | |
| SCHEMBL10252597 | 0.74 | PIK3CD (0.30) | PIK3CD | |
| SCHEMBL18109143 | 0.74 | ALDH1A1 (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654605-B | Bridged heterocyclic group substituted pyrimidine compound and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2022-11-22 | — | — | CN | disclosed |
| EP-4011865-A1 | BRIDGED HETEROCYCLYL-SUBSTITUTED PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | The National Institutes of Pharmaceutical R&D Co., Ltd (CN) | 2022-06-15 | — | — | EP | disclosed |
| WO-2021027647-A1 | BRIDGED HETEROCYCLYL-SUBSTITUTED PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2021-02-18 | — | — | WO | disclosed |