Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750670 | 1.00 | MAPT (0.65) | MAPTALDH1A1NPC1RAB9APOLB | |
| SCHEMBL14351756 | 0.90 | MAPT (0.72) | MAPTALDH1A1NPC1RAB9APOLB | |
| SCHEMBL1337583 | 0.84 | MAPT (0.65) | MAPTALDH1A1NPC1RAB9APOLB | |
| SCHEMBL12786229 | 0.81 | MAPT (0.71) | MAPTALDH1A1NPC1RAB9APOLB | |
| SCHEMBL1983682 | 0.81 | MAPT (0.71) | MAPTALDH1A1NPC1RAB9APOLB | |
| SCHEMBL4788912 | 0.78 | HRH3 (0.44) | MAPTALDH1A1NPC1RAB9APOLB | |
| SCHEMBL4788914 | 0.78 | HRH3 (0.44) | MAPTALDH1A1NPC1RAB9APOLB | |
| SCHEMBL14448351 | 0.77 | MAPT (0.59) | MAPTALDH1A1NPC1RAB9APOLB | |
| SCHEMBL8307478 | 0.76 | NPC1 (0.62) | MAPTALDH1A1NPC1RAB9APOLB | |
| SCHEMBL8550159 | 0.76 | NPC1 (0.62) | MAPTALDH1A1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129129-A1 | HETEROCYCLIC PHENYL CARBAMATES AS NOVEL FAAH-INHIBITORS | KUOPION YLIOPISTO (FI) | 2008-10-30 | — | — | WO | disclosed |