Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788912 | 1.00 | HRH3 (0.44) | HRH3HPGDSMETCCKBRALDH1A1 | |
| SCHEMBL4786913 | 0.80 | CCKBR (0.42) | HRH3CCKBRMAPTSLC6A4HTR6 | |
| SCHEMBL4786920 | 0.80 | CCKBR (0.42) | HRH3CCKBRMAPTSLC6A4HTR6 | |
| SCHEMBL4750670 | 0.78 | MAPT (0.65) | HRH3ALDH1A1MAPTNPC1POLB | |
| SCHEMBL4750672 | 0.78 | MAPT (0.65) | HRH3ALDH1A1MAPTNPC1POLB | |
| SCHEMBL14498457 | 0.72 | CCKBR (0.45) | CCKBRSLC6A4HTR6 | |
| SCHEMBL18409682 | 0.68 | PTPN1 (0.54) | HPGDSMETALDH1A1MAPTPTPN1 | |
| SCHEMBL14351756 | 0.68 | MAPT (0.72) | HRH3ALDH1A1MAPTNPC1POLB | |
| SCHEMBL18409685 | 0.67 | PTPN1 (0.46) | HPGDSMETPTPN1HTR6 | |
| SCHEMBL4748372 | 0.66 | NPC1 (0.50) | MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129129-A1 | HETEROCYCLIC PHENYL CARBAMATES AS NOVEL FAAH-INHIBITORS | KUOPION YLIOPISTO (FI) | 2008-10-30 | — | — | WO | disclosed |