Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681576 | 0.85 | KCNH2 (0.49) | PPARGGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL14306289 | 0.85 | KCNH2 (0.53) | PPARGGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4752742 | 0.84 | PPARG (0.41) | PPARGGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL14524676 | 0.84 | KCNH2 (0.43) | PPARGGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL14305744 | 0.83 | KCNH2 (0.46) | PPARGGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4314841 | 0.83 | KCNH2 (0.47) | KCNH2SMN1; SMN2MEN1KMT2AOPRM1 | |
| SCHEMBL5659035 | 0.82 | KCNH2 (0.41) | PPARGGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL14279078 | 0.81 | HRH3 (0.44) | PPARGGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL20099859 | 0.81 | KCNH2 (0.50) | KCNH2SMN1; SMN2MEN1KMT2AOPRM1 | |
| SCHEMBL14499024 | 0.80 | PPARG (0.41) | PPARGGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| WO-2008147864-A2 | METHODS OF USING PIPERAZINE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-12-04 | — | — | WO | disclosed |
| US-7431793-B2 | Process for bonding substrates or parts and system including cyanoacrylate adhesive and accelerator composition | LOCTITE (R&D) LIMITED (IE) | 2008-10-07 | — | — | US | disclosed |
| US-7431793-B2 | Process for bonding substrates or parts and system including cyanoacrylate adhesive and accelerator composition | LOCTITE (R&D) LIMITED (IE) | 2008-10-07 | — | — | US | disclosed |
| US-20070072096-A1 | Negative curable dye-containing composition, color filter, and method of manufacturing the same | FUJI PHOTO FILM CO., LTD. | 2007-03-29 | — | — | US | disclosed |
| US-7056925-B2 | for example, N-{2-[benzyl(2-hydroxyethyl)amino]-5-bromophenyl)}-N'-(5-cyano-2-pyrazinyl)urea, N-{5-bromo-2-[(2-hydroxy-2-phenylethyl)(methyl)amino]phenyl}-N'-(5-cyano-2-pyrazinyl)urea; anticarcinogenic agents | ABBOTT LABORATORIES (US) | 2006-06-06 | — | — | US | disclosed |
| EP-1534692-A1 | UREA DERIVATIVES AS KINASE INHIBITORS | Abbott Laboratories (US) | 2005-06-01 | — | — | EP | disclosed |
| US-20050000646-A1 | Activator compositions for cyanocrylate adhesives | Henkel IP & Holding GmbH (DE) | 2005-01-06 | — | — | US | disclosed |
| US-20040259885-A1 | Urea kinase inhibitors | ABBVIE INC. | 2004-12-23 | — | — | US | disclosed |
| WO-2004014876-A1 | UREA DERIVATIVES AS KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2004-02-19 | — | — | WO | disclosed |
| US-20040034038-A1 | Urea kinase inhibitors | ABBOTT LABORATORIES | 2004-02-19 | — | — | US | disclosed |
| US-20030229119-A1 | Antagonists of melanin concentrating hormone effects on the melanin concetrating hormone receptor | ABBVIE INC. | 2003-12-11 | — | — | US | disclosed |
| WO-2003070244-A1 | ANTAGONIST OF MELANIN CONCENTRATING HORMONE AND THEIR USES | ABBOTT LABORATORIES (US) | 2003-08-28 | — | — | WO | disclosed |
| WO-2003042311-A1 | ACTIVATOR COMPOSITIONS FOR CYANOACRYLATE ADHESIVES | LOCTITE (R & D) LIMITED (IE) | 2003-05-22 | — | — | WO | disclosed |
| EP-1092732-A2 | Preparation of poly(meth)acrylates by anionic polymerisation in the presence of specific additives in toluene at higher temperatures | RÖHM GMBH (DE) | 2001-04-18 | — | — | EP | disclosed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | disclosed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | disclosed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034038-A1 | Urea kinase inhibitors | UCK2, CMPK1, CDK2 | PPARG 3794/4885GABRA1 4488/4885GABRG2 4459/4885 |
| US-20030229119-A1 | Antagonists of melanin concentrating hormone effects on the melanin concetrating hormone receptor | MCHR1, MCHR2, MC1R | PPARG 1750/4885GABRA1 90/4885GABRG2 132/4885 |
| US-20040259885-A1 | Urea kinase inhibitors | UCK2, CMPK1, CDK2 | PPARG 3794/4885GABRA1 4488/4885GABRG2 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.