Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.38 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.38 |
| ▸ | GGH | Q92820 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22316563 | 0.87 | CTSK (0.38) | FOLH1NAALAD2RIMKLAGGHMEN1 | |
| SCHEMBL27400896 | 0.85 | FOLH1 (0.39) | FOLH1NAALAD2RIMKLAGGHMEN1 | |
| SCHEMBL13863589 | 0.85 | FOLH1 (0.39) | FOLH1NAALAD2RIMKLAGGHMEN1 | |
| SCHEMBL5172322 | 0.83 | ANPEP (0.42) | FOLH1NAALAD2RIMKLAGGHMEN1 | |
| SCHEMBL12267040 | 0.83 | ANPEP (0.42) | FOLH1NAALAD2RIMKLAGGHMEN1 | |
| SCHEMBL22316568 | 0.83 | ANPEP (0.42) | FOLH1NAALAD2RIMKLAGGHMEN1 | |
| SCHEMBL12626915 | 0.81 | FOLH1 (0.43) | FOLH1NAALAD2RIMKLAGGHMEN1 | |
| SCHEMBL4363123 | 0.81 | FOLH1 (0.43) | FOLH1NAALAD2RIMKLAGGHMEN1 | |
| SCHEMBL6948884 | 0.80 | FOLH1 (0.42) | FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL22271661 | 0.80 | FOLH1 (0.38) | FOLH1NAALAD2RIMKLAGGHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008145609-A1 | METHOD OF MAKING COVALENT CONJUGATES WITH HIS-TAGGED PROTEINS | NOVARTIS AG (CH) | 2008-12-04 | — | — | WO | disclosed |