Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.44 |
| ▸ | SRC | P12931 | 6/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468501 | 0.79 | KDR (0.48) | KDRPDGFRBSRCFGFR1ALDH1A1 | |
| SCHEMBL2559154 | 0.78 | KDR (0.47) | KDRPDGFRBSRCFGFR1ALDH1A1 | |
| SCHEMBL6444716 | 0.71 | ALDH1A1 (0.50) | KDRPDGFRBSRCFGFR1ALDH1A1 | |
| SCHEMBL7959781 | 0.67 | ALDH1A1 (0.46) | KDRPDGFRBSRCFGFR1ALDH1A1 | |
| SCHEMBL22396741 | 0.67 | ALDH1A1 (0.50) | KDRPDGFRBSRCFGFR1ALDH1A1 | |
| SCHEMBL21284842 | 0.65 | ALDH1A1 (0.46) | KDRPDGFRBSRCFGFR1ALDH1A1 | |
| SCHEMBL21040050 | 0.65 | ALDH1A1 (0.46) | KDRPDGFRBSRCFGFR1ALDH1A1 | |
| SCHEMBL21040048 | 0.65 | ALDH1A1 (0.46) | KDRPDGFRBSRCFGFR1ALDH1A1 | |
| SCHEMBL21040049 | 0.65 | ALDH1A1 (0.46) | KDRPDGFRBSRCFGFR1ALDH1A1 | |
| SCHEMBL19706853 | 0.65 | ALDH1A1 (0.46) | KDRPDGFRBSRCFGFR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147246-A1 | CATALYST FOR DEHYDROGENATION OF 4,5,6,7 TETRAHYDROINDOLE INTO INDOLE AND METHOD FOR PREPARING THEREOF | A.E. FAVORSKY IRKUTSK INSTITUTE OF CHEMISTRY SIBERIAN BRANCH RUSSIAN ACADEMY OF SCIENCES (IRIH SB RAS) (RU) | 2008-12-04 | — | — | WO | disclosed |