Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11586710 | 0.93 | TSHR (0.58) | TSHRALDH1A1GAAPKMSMN1; SMN2 | |
| SCHEMBL11586550 | 0.93 | TSHR (0.58) | TSHRALDH1A1GAAPKMSMN1; SMN2 | |
| SCHEMBL10451043 | 0.93 | TSHR (0.58) | TSHRALDH1A1GAAPKMSMN1; SMN2 | |
| SCHEMBL463195 | 0.79 | TSHR (0.70) | TSHRALDH1A1GAAPKMSMN1; SMN2 | |
| SCHEMBL153651 | 0.79 | TSHR (0.77) | TSHRALDH1A1GAAPKMSMN1; SMN2 | |
| SCHEMBL18432690 | 0.79 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL7708490 | 0.79 | TSHR (0.56) | TSHRALDH1A1GAAPKMSMN1; SMN2 | |
| SCHEMBL720609 | 0.78 | TSHR (0.42) | TSHRALDH1A1GAAPKMSMN1; SMN2 | |
| SCHEMBL180289 | 0.77 | TSHR (0.81) | TSHRALDH1A1GAAPKMSMN1; SMN2 | |
| SCHEMBL5392962 | 0.77 | TSHR (0.81) | TSHRALDH1A1GAAPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132541-A2 | CONJUGATES OF 2-FLUORO-2-DEOXY-GLUCOSE AND THEIR USES AS ANTI CANCER AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-11-06 | — | — | WO | disclosed |