Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27745762 | 0.82 | TSHR (0.41) | TSHRTDP1PKMSMN1; SMN2CYP3A4 | |
| SCHEMBL10816577 | 0.80 | CYP3A4 (0.32) | TSHRCYP3A4MAPTCACNA1BAPBA1 | |
| SCHEMBL4751050 | 0.78 | TSHR (0.53) | TSHRTDP1PKMSMN1; SMN2CYP3A4 | |
| SCHEMBL18432679 | 0.76 | TSHR (0.52) | TSHRSMN1; SMN2CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL11586550 | 0.75 | TSHR (0.58) | TSHRTDP1PKMSMN1; SMN2CYP3A4 | |
| SCHEMBL11586710 | 0.75 | TSHR (0.58) | TSHRTDP1PKMSMN1; SMN2CYP3A4 | |
| SCHEMBL10451043 | 0.75 | TSHR (0.58) | TSHRTDP1PKMSMN1; SMN2CYP3A4 | |
| SCHEMBL28233804 | 0.75 | — | — | |
| SCHEMBL48624 | 0.72 | — | — | |
| Benzene SCHEMBL28123622 | 0.72 | NPSR1 (0.43) | TSHRTDP1PKMSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10591497-B2 | Immunoassay for synthetic cannabinoids of the adamantyl indazole/indole-3-carboxamide family | RANDOX LABORATORIES LTD. (GB) | 2020-03-17 | — | — | US | disclosed |
| EP-2950103-B1 | IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE 3-ADAMANTANYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY | RANDOX LABORATORIES LTD (GB) | 2018-10-17 | — | — | EP | disclosed |
| US-20150346227-A1 | IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE ADAMANTYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY | NORTHERN BANK LIMITED (IE) | 2015-12-03 | — | — | US | disclosed |
| EP-2950103-A1 | IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE 3-ADAMANTANYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY | Randox Laboratories Ltd. (GB) | 2015-12-02 | — | — | EP | disclosed |
| US-8796324-B2 | Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-20120238607-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-09-20 | — | — | US | disclosed |
| US-8202895-B2 | Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-06-19 | — | — | US | disclosed |
| US-20120053218-A1 | TRIAZOLE DERIVATIVES AS VASOPRESSIN-RECEPTOR INHIBITORS FOR TREATING CARDIAC INSUFFICIENCY | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-01 | — | — | US | disclosed |
| EP-1362067-B1 | DURABLE REFINISH COATING | BASF CORP (US) | 2011-03-30 | — | — | EP | disclosed |
| US-20100261771-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-10-14 | — | — | US | disclosed |
| WO-2002050199-A2 | COATING | BASF CORPORATION, PLEASE SEE GENERAL APPOINTMENT OF REPRESENTATIVE (US) | 2002-06-27 | — | — | WO | disclosed |
| EP-0718290-B1 | Carboxyalkyl heterocyclic derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2002-04-17 | — | — | EP | disclosed |
| EP-1141149-A1 | COATING COMPOSITIONS CONTAINING MODIFIED CARBAMATE-FUNCTIONAL POLYACRYLIC BINDERS | Basf Corporation (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6106951-A | CONVERTING HYDROXYL GROUPS OF ACRYLIC RESIN INTO NEW GROUPS; COMBINING WITH AMINOPLAST CROSSLINKER TO FORM COATING MIXTURE; APPLYING COATING MIXTURE TO SUBSTRATE AND CURING TO PRODUCE CURED COATING | BASF CORPORATION (US) | 2000-08-22 | — | — | US | disclosed |
| WO-2000031195-A1 | COATING COMPOSITIONS CONTAINING MODIFIED CARBAMATE-FUNCTIONAL POLYACRYLIC BINDERS | BASF CORPORATION (US) | 2000-06-02 | — | — | WO | disclosed |
| US-5912261-A | ANTIDIABETIC AGENTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1999-06-15 | — | — | US | disclosed |
| EP-0718290-A1 | Carboxyalkyl heterocyclic derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5304479-A | Phencyclidine compounds and assays for its determination | DIAGNOSTIC REAGENTS, INC. (US) | 1994-04-19 | — | — | US | disclosed |
| EP-0094776-B1 | NOVEL PROCESS FOR THE PREPARATION OF BIOTIN | PFIZER INC. (US) | 1988-06-22 | — | — | EP | disclosed |
| EP-0094776-A2 | Novel process for the preparation of biotin | PFIZER INC. (US) | 1983-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238607-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | AADAC, NAT1, TNNT2 | TSHR 2591/4885TDP1 1724/4885PKM 279/4885 |
| US-20120053218-A1 | TRIAZOLE DERIVATIVES AS VASOPRESSIN-RECEPTOR INHIBITORS FOR TREATING CARDIAC INSUFFICIENCY | AVPR2, AVPR1B, AVPR1A | TSHR 78/4885TDP1 1637/4885PKM 707/4885 |
| US-20100261771-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | AADAC, NAT1, TNNT2 | TSHR 2591/4885TDP1 1724/4885PKM 279/4885 |
| US-20150346227-A1 | IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE ADAMANTYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY | CNR2, CNR1, IDO1 | TSHR 1266/4885TDP1 3525/4885PKM 4870/4885 |
| US-10591497-B2 | Immunoassay for synthetic cannabinoids of the adamantyl indazole/indole-3-carboxamide family | CNR2, CNR1, IDO1 | TSHR 1266/4885TDP1 3525/4885PKM 4870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.