Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401795 | 0.94 | TSHR (0.52) | TSHRALDH1A1KMT2APABPC1HTT | |
| SCHEMBL1969772 | 0.85 | TSHR (0.55) | TSHRALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL11582516 | 0.83 | QPCT (0.54) | TSHRALDH1A1KMT2APABPC1HTT | |
| SCHEMBL2991298 | 0.80 | MGLL (0.47) | TSHRALDH1A1GSK3AGSK3B | |
| SCHEMBL14761839 | 0.80 | GSK3A (0.46) | TSHRALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL10976405 | 0.80 | TSHR (0.46) | TSHRALDH1A1KMT2AHTTLMNA | |
| SCHEMBL9805873 | 0.78 | MGLL (0.50) | TSHRGSK3AGSK3B | |
| SCHEMBL9805934 | 0.78 | MGLL (0.50) | TSHRGSK3AGSK3B | |
| SCHEMBL9805920 | 0.78 | MGLL (0.50) | TSHRGSK3AGSK3B | |
| SCHEMBL9805904 | 0.78 | MGLL (0.50) | TSHRGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008136841-A1 | POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-11-13 | — | — | WO | disclosed |