Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750269 | 0.91 | HTR2A (0.41) | HTR2AHTR2CHTR2BHTR1ACYP1A2 | |
| SCHEMBL25143222 | 0.88 | MTNR1A (0.45) | HTR2AHTR2CHTR2BHTR1ACYP1A2 | |
| SCHEMBL4750246 | 0.84 | SMN1; SMN2 (0.45) | HTR2AHTR2CLMNATAAR1 | |
| SCHEMBL5355957 | 0.74 | PDE4A (0.46) | HTR2AHTR2CLMNAMTNR1AMTNR1B | |
| SCHEMBL4982275 | 0.74 | PDE4A (0.57) | HTR2AHTR2CHTR2BHTR1ACYP1A2 | |
| SCHEMBL661243 | 0.72 | MGAM (0.42) | HTR2AHTR2CHTR2BHTR1ACYP1A2 | |
| SCHEMBL5350260 | 0.72 | HTR2A (0.43) | HTR2AHTR2CLMNAMTNR1AMTNR1B | |
| SCHEMBL3391657 | 0.72 | HTR2A (0.52) | HTR2AHTR2CHTR2BHTR1ACYP1A2 | |
| SCHEMBL21798808 | 0.71 | TAAR1 (0.52) | HTR2AHTR2CCYP3A4HMGCRPDE4A | |
| SCHEMBL4748125 | 0.71 | STAT3 (0.51) | CYP1A2CYP3A4CYP2D6PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124878-A1 | NON-STEROIDAL COMPOUNDS | CRYPTOPHARMA PTY LTD (AU) | 2008-10-23 | — | — | WO | disclosed |