Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475451 | 0.75 | — | — | |
| SCHEMBL29035804 | 0.71 | KMT2A (0.36) | HSP90AB1TSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL29790931 | 0.68 | HSP90AB1 (0.37) | HSP90AB1CYP4F2CYP4A11TSHRHSD17B10 | |
| SCHEMBL29288243 | 0.67 | — | — | |
| SCHEMBL4751568 | 0.67 | HSP90AB1 (0.39) | HSP90AB1CYP4F2CYP4A11TSHRHSD17B10 | |
| SCHEMBL27668360 | 0.66 | — | — | |
| SCHEMBL2237455 | 0.64 | — | — | |
| SCHEMBL21891794 | 0.62 | HSP90AB1 (0.75) | HSP90AB1CYP4F2CYP4A11TSHRHSD17B10 | |
| SCHEMBL14354674 | 0.62 | HSP90AB1 (0.56) | HSP90AB1CYP4F2CYP4A11TSHRHSD17B10 | |
| SCHEMBL4113212 | 0.62 | CYP4F2 (0.76) | HSP90AB1CYP4F2CYP4A11KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008144602-A1 | DEUTERATED ZAMIFENACIN DERIVATIVES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |