Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751569 | 0.71 | HSP90AB1 (0.39) | KMT2AKDM4EMEN1SMN1; SMN2TSHR | |
| SCHEMBL4719477 | 0.62 | KMT2A (0.33) | KMT2AKDM4EMEN1SMN1; SMN2TSHR | |
| SCHEMBL16752652 | 0.62 | POLB (0.49) | KMT2AKDM4EMEN1SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL11878758 | 0.61 | KMT2A (0.32) | KMT2AKDM4EMEN1SMN1; SMN2TSHR | |
| SCHEMBL1871683 | 0.61 | GAA (0.59) | KMT2AKDM4EMEN1TSHRHSD17B10 | |
| SCHEMBL658053 | 0.61 | LMNA (0.54) | KMT2AKDM4EMEN1SMN1; SMN2TSHR | |
| SCHEMBL9780021 | 0.59 | KMT2A (0.57) | KMT2AKDM4EMEN1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL76327 | 0.59 | LMNA (0.53) | KMT2AKDM4EMEN1SMN1; SMN2TSHR | |
| Benzene SCHEMBL28330086 | 0.59 | LMNA (0.53) | KMT2AKDM4EMEN1SMN1; SMN2TSHR | |
| SCHEMBL9796041 | 0.59 | MAPT (0.50) | KMT2AKDM4EMEN1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116574105-A | Quinoline derivatives having indoleamine-2, 3-dioxygenase inhibitory activity | 深圳微芯生物科技股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-110950842-B | Quinoline derivatives having indoleamine-2, 3-dioxygenase inhibitory activity | 深圳微芯生物科技股份有限公司 | 2023-06-20 | — | — | CN | disclosed |