⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608733 | 0.70 | — | — | |
| Thioglycin SCHEMBL358229 | 0.70 | — | — | |
| Thioglycin SCHEMBL29548409 | 0.67 | — | — | |
| SCHEMBL28750012 | 0.67 | — | — | |
| Bromide SCHEMBL10873565 | 0.67 | — | — | |
| SCHEMBL5144336 | 0.67 | — | — | |
| SCHEMBL8712166 | 0.67 | — | — | |
| SCHEMBL5005836 | 0.65 | — | — | |
| SCHEMBL19053 | 0.65 | — | — | |
| SCHEMBL28510462 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046235-A9 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2012-02-23 | — | — | US | claimed |
| EP-1933878-B1 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DE GMBH (DE) | 2012-02-01 | — | — | EP | claimed |
| EP-2279752-A2 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | Fresenius Kabi Deutschland GmbH (DE) | 2011-02-02 | — | — | EP | claimed |
| US-20100311670-A1 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-12-09 | — | — | US | claimed |
| US-20080207562-A1 | Conjugates of Hydroxyalkyl Starch and Active Substance, Prepared by Chemical Ligation Via Thiazolidine | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2008-08-28 | — | — | US | claimed |
| EP-1933878-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | Fresenius Kabi Deutschland GmbH (DE) | 2008-06-25 | — | — | EP | claimed |
| WO-2007031266-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2007-03-22 | — | — | WO | claimed |
| EP-1762250-A1 | Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine | Fresenius Kabi Deutschland GmbH (DE) | 2007-03-14 | — | — | EP | claimed |
| EP-1732609-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND A PROTEIN | Fresenius Kabi Deutschland GmbH (DE) | 2006-12-20 | — | — | EP | claimed |
| WO-2005092391-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND A PROTEIN | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2005-10-06 | — | — | WO | claimed |
| US-20120046235-A9 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2012-02-23 | — | — | US | disclosed |
| EP-1933878-B1 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DE GMBH (DE) | 2012-02-01 | — | — | EP | disclosed |
| EP-2279752-A2 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | Fresenius Kabi Deutschland GmbH (DE) | 2011-02-02 | — | — | EP | disclosed |
| US-20100311670-A1 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-12-09 | — | — | US | disclosed |
| US-20080207562-A1 | Conjugates of Hydroxyalkyl Starch and Active Substance, Prepared by Chemical Ligation Via Thiazolidine | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2008-08-28 | — | — | US | disclosed |
| EP-1933878-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | Fresenius Kabi Deutschland GmbH (DE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007031266-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2007-03-22 | — | — | WO | disclosed |
| EP-1762250-A1 | Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine | Fresenius Kabi Deutschland GmbH (DE) | 2007-03-14 | — | — | EP | disclosed |