SCHEMBL608733

SCHEMBL608733

NCC(N)=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL10873565 0.95
SCHEMBL2396665 0.70
SCHEMBL4969205 0.70
Thiourea SCHEMBL28113885 0.70
SCHEMBL475159 0.70
SCHEMBL3067654 0.70
SCHEMBL1512939 0.70
Thioglycin SCHEMBL358229 0.70
Glycine SCHEMBL22206093 0.68
SCHEMBL2696159 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4099773-A None JP disclosed
CN-117344339-A Nickel-molybdenum-sulfur electrocatalyst and preparation method thereof 华电电力科学研究院有限公司 2024-01-05 CN disclosed
US-11820763-B2 Bromophenol-pyrazoline compound and synthesis method and use thereof Lead High Technology (QingDao) Co., Ltd (CN) 2023-11-21 US disclosed
US-11753405-B2 1,3,4-thiadiazole compounds and their use in treating cancer CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2023-09-12 US disclosed
US-11752133-B2 Use of bromophenol-pyrazoline compounds in the treatment of porcine coronavirus diseases Shandong Linghai Biotechnology Co., Ltd. (CN) 2023-09-12 US disclosed
US-11725080-B2 Schiff base oligomers THE BOEING COMPANY (US) 2023-08-15 US disclosed
US-11713374-B2 Schiff base oligomers THE BOEING COMPANY (US) 2023-08-01 US disclosed
US-11708332-B2 Human plasma kallikrein inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2023-07-25 US disclosed
US-11708333-B2 Human plasma kallikrein inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2023-07-25 US disclosed
US-11685721-B2 Human plasma kallikrein inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2023-06-27 US disclosed
EP-0083186-B1 THIAZOLE DERIVATIVES AS H2-RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1988-05-11 EP disclosed
EP-0091220-B1 THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ELI LILLY AND COMPANY (US) 1987-05-13 EP disclosed
EP-0049618-B1 IMPROVEMENTS IN OR RELATING TO 2,4-DISUBSTITUTED THIAZOLE DERIVATIVES ELI LILLY AND COMPANY (US) 1985-08-14 EP disclosed
US-4474794-A N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds ELI LILLY AND COMPANY (US) 1984-10-02 US disclosed
US-4468399-A ANTISECRETORY AGENTS, ANTIHISTAMINES ELI LILLY AND COMPANY (US) 1984-08-28 US disclosed
EP-0091220-A2 Thiazole derivatives, process for their preparation and pharmaceutical compositions containing them ELI LILLY AND COMPANY (US) 1983-10-12 EP disclosed
EP-0083186-A2 Thiazole derivatives as H2-receptor antagonists ELI LILLY AND COMPANY (US) 1983-07-06 EP disclosed
US-4382090-A N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds ELI LILLY AND COMPANY (US) 1983-05-03 US disclosed
US-4375547-A ANTIHISTAMINES, 'I RECEPTOR ANTAGONISTS, ANTISECRETORY AGENTS ELI LILLY AND COMPANY (US) 1983-03-01 US disclosed
EP-0049618-A1 Improvements in or relating to 2,4-disubstituted thiazole derivatives ELI LILLY AND COMPANY (US) 1982-04-14 EP disclosed