Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 8/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | ACACA | Q13085 | 4/20 | 0.40 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751768 | 1.00 | KMT2A (0.48) | KMT2AACACBDRD2ACACAPBK | |
| SCHEMBL12017949 | 0.85 | ACACB (0.49) | KMT2AACACBDRD2ACACAPBK | |
| SCHEMBL190838 | 0.81 | KMT2A (0.56) | KMT2AACACBDRD2ACACAEPHX1 | |
| SCHEMBL3942686 | 0.81 | KMT2A (0.56) | KMT2AACACBDRD2ACACAEPHX1 | |
| SCHEMBL3816616 | 0.81 | KMT2A (0.56) | KMT2AACACBDRD2ACACAEPHX1 | |
| SCHEMBL4377073 | 0.81 | KMT2A (0.56) | KMT2AACACBDRD2ACACAEPHX1 | |
| SCHEMBL5126100 | 0.81 | KMT2A (0.52) | KMT2AACACBDRD2ACACAPBK | |
| SCHEMBL11934704 | 0.79 | NPY5R (0.47) | — | |
| SCHEMBL18534331 | 0.79 | EPHX1 (0.52) | KMT2AACACBDRD2ACACAPBK | |
| SCHEMBL14408855 | 0.79 | KMT2A (0.49) | KMT2AACACBDRD2ACACAPBK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134228-A1 | BENZOXAZOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 2008-11-06 | — | — | WO | disclosed |