Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30836782 | 0.88 | KMT2A (0.40) | KMT2AALDH1A1ADORA3CYP1A2GAA | |
| SCHEMBL2522852 | 0.88 | PDCD1 (0.43) | KMT2AALDH1A1ADORA3CYP1A2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27136948 | 0.87 | PDCD1 (0.42) | KMT2AALDH1A1ADORA3CYP1A2L3MBTL1 | |
| SCHEMBL2929174 | 0.83 | NPC1 (0.41) | KMT2AALDH1A1CYP1A2L3MBTL1GAA | |
| SCHEMBL2928372 | 0.82 | NPC1 (0.43) | KMT2AALDH1A1CYP1A2L3MBTL1LMNA | |
| SCHEMBL6379433 | 0.81 | NPC1 (0.44) | KMT2AALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL2519257 | 0.81 | ALDH1A1 (0.39) | KMT2AALDH1A1ADORA3CYP1A2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL16100186 | 0.80 | KMT2A (0.40) | KMT2AALDH1A1ADORA3CYP1A2L3MBTL1 | |
| SCHEMBL3309074 | 0.76 | CYP1A2 (0.40) | KMT2AALDH1A1CYP1A2GAAKDM4E | |
| SCHEMBL3551607 | 0.76 | PIK3CA (0.44) | KMT2AALDH1A1CYP1A2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135526-A1 | CARBOXYLIC ACID AMIDES AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-13 | — | — | WO | disclosed |