Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751949 | 0.78 | HTT (0.42) | HTTATMMGLLHRH3GPR119 | |
| SCHEMBL12719014 | 0.73 | CYP19A1 (0.40) | HTTATMCYP19A1EPHX2CACNA1C | |
| SCHEMBL18734148 | 0.72 | CYP19A1 (0.49) | CYP19A1GPR88 | |
| SCHEMBL31208153 | 0.71 | HTT (0.53) | HTTATMGPR119IRAK4MAPK1 | |
| SCHEMBL12719013 | 0.70 | CYP19A1 (0.40) | HTTATMCYP19A1EPHX2CACNA1C | |
| SCHEMBL30896970 | 0.69 | CA12 (0.45) | HTTATMCYP19A1EPHX2CACNA1C | |
| SCHEMBL4749714 | 0.69 | HTT (0.36) | HTTATMMGLLHRH3PLA2G7 | |
| SCHEMBL24438094 | 0.68 | CYP19A1 (0.46) | HTTATMCYP19A1EPHX2CACNA1C | |
| SCHEMBL12172122 | 0.68 | CYP19A1 (0.56) | HTTATMCYP19A1GPR88HRH3 | |
| SCHEMBL24482326 | 0.67 | CYP19A1 (0.44) | HTTATMCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |