Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751987 | 0.78 | HTT (0.43) | HTTATMKDM1AGPR119MAPK1 | |
| SCHEMBL14262405 | 0.74 | ACHE (0.36) | ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL4749714 | 0.71 | HTT (0.36) | HTTATMKDM1AKMT2AL3MBTL1 | |
| SCHEMBL4753615 | 0.67 | HDAC8 (0.41) | HTTKMT2ASMN1; SMN2MEN1MGLL | |
| SCHEMBL22021946 | 0.66 | ACHE (0.35) | ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL4303680 | 0.64 | HSD17B10 (0.47) | HTTALDH1A1MGLLFAAH | |
| SCHEMBL4297220 | 0.64 | MGLL (0.45) | MAPK1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL27979621 | 0.62 | — | — | |
| SCHEMBL26317513 | 0.62 | TSHR (0.43) | HTTKDM1AGPR119ALDH1A1SMN1; SMN2 | |
| SCHEMBL3404701 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |