Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749428 | 1.00 | NOS1 (0.39) | NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL5087 | 1.00 | NOS1 (0.39) | NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL6997706 | 1.00 | NOS1 (0.39) | NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL7001568 | 1.00 | NOS1 (0.39) | NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL7845410 | 1.00 | NOS1 (0.39) | NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL7853380 | 0.97 | NOS1 (0.41) | NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL1884259 | 0.97 | NOS1 (0.41) | NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL1695905 | 0.97 | NOS1 (0.41) | NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL310611 | 0.97 | NOS1 (0.41) | NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL9050134 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |