Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.39 |
| ▸ | PI4KA | P42356 | 4/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | AHCY | P23526 | 3/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24196376 | 0.76 | ADORA2A (0.65) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9469908 | 0.74 | ADORA2A (0.46) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9786770 | 0.73 | ADORA2A (0.49) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| Hydrochloric Acid SCHEMBL31591398 | 0.73 | ADORA2A (0.49) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL14037522 | 0.72 | AHCY (0.48) | PDE4APDE4BPDE4CPDE4DADORA2B | |
| SCHEMBL11400740 | 0.72 | ADORA2A (0.68) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL130820 | 0.72 | PI4KA (0.43) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL8885246 | 0.71 | ADCY5 (0.45) | PDE4APDE4BPDE4CPDE4DAHCY | |
| SCHEMBL4352091 | 0.71 | ADCY5 (0.45) | PDE4APDE4BPDE4CPDE4DAHCY | |
| SCHEMBL9685991 | 0.71 | ADORA2A (0.50) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131502-A2 | ANTIVIRAL COMPOUNDS OF THE ADAMANTANE TYPE | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | claimed |
| WO-2008131502-A2 | ANTIVIRAL COMPOUNDS OF THE ADAMANTANE TYPE | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | disclosed |