Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.54 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | MC5R | P33032 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | MC1R | Q01726 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4678742 | 0.86 | MC4R (0.58) | MC4RSMYD3MC5RMC3RMC1R | |
| SCHEMBL6252350 | 0.86 | MC4R (0.58) | MC4RSMYD3MC5RMC3RMC1R | |
| SCHEMBL4752273 | 0.85 | MC4R (0.43) | MC4RMC5RMC3RMC1R | |
| SCHEMBL4697531 | 0.84 | MC4R (0.61) | MC4R | |
| SCHEMBL4697587 | 0.83 | MC4R (0.56) | MC4RSMYD3MC5RMC3RMC1R | |
| SCHEMBL14559908 | 0.81 | MC4R (0.67) | MC4RSMYD3MC5RMC3RMC1R | |
| SCHEMBL14591463 | 0.81 | MC4R (0.66) | MC4RSMYD3MC5RMC3RMC1R | |
| SCHEMBL4698206 | 0.81 | MC4R (0.65) | MC4RSMYD3MC5RMC3RMC1R | |
| SCHEMBL14591290 | 0.81 | MC4R (0.57) | MC4RSMYD3MC5RMC3RMC1R | |
| SCHEMBL4700096 | 0.81 | MC4R (0.57) | MC4RSMYD3MC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM INC (US) | 2008-01-02 | — | — | EP | claimed |