Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.43 |
| ▸ | MC5R | P33032 | 4/20 | 0.39 |
| ▸ | MC3R | P41968 | 4/20 | 0.39 |
| ▸ | MC1R | Q01726 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4678746 | 0.86 | TACR1 (0.48) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL4752271 | 0.85 | MC4R (0.54) | MC4RMC5RMC3RMC1R | |
| SCHEMBL4697534 | 0.84 | MC4R (0.59) | MC4R | |
| SCHEMBL4697626 | 0.83 | MC4R (0.46) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL4700100 | 0.81 | MC4R (0.45) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL4698209 | 0.81 | MC4R (0.47) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL4698459 | 0.81 | MC4R (0.48) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL4698090 | 0.81 | MC4R (0.44) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL4675958 | 0.81 | MC4R (0.44) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL4697991 | 0.80 | MC4R (0.41) | MC4RMC5RMC3RMC1RCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM INC (US) | 2008-01-02 | — | — | EP | claimed |