Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.58 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12247341 | 0.84 | HDAC4 (0.56) | ANPEPENPEPMRGPRX4FOLH1PARP1 | |
| SCHEMBL12247344 | 0.84 | HDAC4 (0.56) | ANPEPENPEPMRGPRX4FOLH1PARP1 | |
| SCHEMBL1320105 | 0.84 | ANPEP (0.56) | ANPEPENPEPMRGPRX4FOLH1PARP1 | |
| SCHEMBL10174229 | 0.84 | HDAC4 (0.56) | ANPEPENPEPMRGPRX4FOLH1PARP1 | |
| SCHEMBL16429230 | 0.83 | FOLH1 (0.55) | ANPEPENPEPMRGPRX4FOLH1PARP1 | |
| SCHEMBL6014463 | 0.83 | ANPEP (0.59) | ANPEPENPEPMRGPRX4PARP1CA1 | |
| SCHEMBL6014468 | 0.83 | ANPEP (0.51) | ANPEPENPEPMRGPRX4PARP1CA1 | |
| SCHEMBL7357638 | 0.83 | ANPEP (0.54) | ANPEPENPEPMRGPRX4FOLH1PARP1 | |
| SCHEMBL24483458 | 0.82 | TAAR1 (0.46) | ANPEPENPEPTAAR1CA1CA2 | |
| SCHEMBL4446181 | 0.82 | LOXL2 (0.62) | TAAR1PARP1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135526-A1 | CARBOXYLIC ACID AMIDES AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-13 | — | — | WO | disclosed |