Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 9/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.37 |
| ▸ | CDK2AP1 | O14519 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1866030 | 0.89 | REN (0.46) | RENMEN1KMT2ADRD2 | |
| SCHEMBL1866028 | 0.89 | REN (0.46) | RENMEN1KMT2ADRD2 | |
| SCHEMBL1861229 | 0.88 | SCN5A (0.43) | RENMEN1KMT2A | |
| SCHEMBL3597925 | 0.88 | REN (0.40) | RENMEN1KMT2ADRD2 | |
| SCHEMBL3600940 | 0.88 | SCN5A (0.43) | RENMEN1KMT2A | |
| SCHEMBL1861227 | 0.88 | SCN5A (0.43) | RENMEN1KMT2A | |
| SCHEMBL1867384 | 0.88 | REN (0.40) | RENMEN1KMT2ADRD2 | |
| SCHEMBL1867383 | 0.88 | REN (0.40) | RENMEN1KMT2ADRD2 | |
| SCHEMBL3597921 | 0.88 | REN (0.40) | RENMEN1KMT2ADRD2 | |
| SCHEMBL3616993 | 0.88 | REN (0.42) | RENCHEK1CDK2AP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156832-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |