Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4304424 | 0.82 | KDM1A (0.48) | KDM1AKDM1BHTR2CHTR2BCYP19A1 | |
| SCHEMBL29749063 | 0.82 | KDM1A (0.48) | KDM1AKDM1BHTR2CHTR2BCYP19A1 | |
| SCHEMBL30370466 | 0.82 | KDM1A (0.48) | KDM1AKDM1BHTR2CHTR2BCYP19A1 | |
| SCHEMBL937009 | 0.82 | KDM1A (0.48) | KDM1AKDM1BHTR2CHTR2BCYP19A1 | |
| SCHEMBL4753990 | 0.79 | HTR2A (0.41) | KDM1AHTR2CHTR2BTSHRHTR6 | |
| SCHEMBL4750478 | 0.79 | HTR2C (0.42) | KDM1AHTR2CHTR2BGAATSHR | |
| SCHEMBL3630441 | 0.73 | TSHR (0.64) | KDM1AHTR2CHTR2BTSHRHSD17B10 | |
| SCHEMBL28759921 | 0.71 | KDM1A (0.45) | KDM1AKDM1BHTR2CHTR2BCYP19A1 | |
| SCHEMBL11358035 | 0.69 | KDM1A (0.41) | KDM1AKDM1BHTR2CHTR2BCYP19A1 | |
| SCHEMBL28204861 | 0.68 | HTR2C (0.41) | KDM1AKDM1BHTR2CHTR2BCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |