⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57457 | 0.84 | — | — | |
| SCHEMBL7300548 | 0.84 | — | — | |
| Ether SCHEMBL8961469 | 0.81 | ALDH1A1 (0.38) | — | |
| SCHEMBL14673473 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL28646303 | 0.81 | — | — | |
| SCHEMBL5694827 | 0.81 | ALDH1A1 (0.42) | — | |
| SCHEMBL9347043 | 0.80 | ALDH1A1 (0.33) | — | |
| SCHEMBL14672997 | 0.79 | MEN1 (0.32) | — | |
| SCHEMBL14673540 | 0.79 | MEN1 (0.32) | — | |
| SCHEMBL14673503 | 0.79 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017147410-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2017-08-31 | — | — | WO | disclosed |
| US-8936859-B2 | Cyclophosphazene compound, lubricant comprising same, and magnetic disk | MORESCO CORPORATION (JP) | 2015-01-20 | — | — | US | disclosed |
| EP-2565198-B1 | CYCLOPHOSPHAZENE COMPOUND, LUBRICANT COMPRISING SAME, AND MAGNETIC DISK | MORESCO CORP (JP) | 2014-09-10 | — | — | EP | disclosed |
| US-20130157976-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | CLAUS ECKHARD (DE) | 2013-06-20 | — | — | US | disclosed |
| EP-2565198-A1 | CYCLOPHOSPHAZENE COMPOUND, LUBRICANT COMPRISING SAME, AND MAGNETIC DISK | MORESCO Corporation (JP) | 2013-03-06 | — | — | EP | disclosed |
| US-20130034749-A1 | CYCLOPHOSPHAZENE COMPOUND, LUBRICANT COMPRISING SAME, AND MAGNETIC DISK | MORESCO CORPORATION (JP) | 2013-02-07 | — | — | US | disclosed |
| US-20120252760-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ZENTARIS GMBH (DE) | 2012-10-04 | — | — | US | disclosed |
| US-8217042-B2 | Pyridopyrazines and their use as modulators of kinases | ZENTARIS GMBH (DE) | 2012-07-10 | — | — | US | disclosed |
| EP-1957487-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | AEterna Zentaris GmbH (DE) | 2008-08-20 | — | — | EP | disclosed |
| US-20070149484-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ZENTARIS GMBH (DE) | 2007-06-28 | — | — | US | disclosed |
| WO-2007054556-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ÆTERNA ZENTARIS GMBH (DE) | 2007-05-18 | — | — | WO | disclosed |