Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751089 | 0.86 | ALDH1A1 (0.32) | ALDH1A1TSHRSMN1; SMN2TDP1 | |
| SCHEMBL4751359 | 0.77 | TSHR (0.47) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL11087167 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL49463 | 0.71 | ALDH1A1 (0.52) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL4753547 | 0.69 | — | — | |
| SCHEMBL4753551 | 0.69 | ALDH1A1 (0.35) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL4751352 | 0.69 | ALDH1A1 (0.35) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL4751115 | 0.68 | — | — | |
| SCHEMBL16944227 | 0.68 | TSHR (0.48) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL7519039 | 0.68 | ALDH1A1 (0.49) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149375-A1 | IMPROVED ORGANOSILICON COMPOUNDS | RANKA, SEEMA, AJAY (IN) | 2008-12-11 | — | — | WO | claimed |
| US-20080009644-A1 | Organosilicon Compounds | ZYDEX INDUSTRIES | 2008-01-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009644-A1 | Organosilicon Compounds | CUL1, CUL3, MGAM | ALDH1A1 1076/4885TSHR 4731/4885SMN1; SMN2 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.