Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954901 | 0.84 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1011657 | 0.82 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7879531 | 0.78 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29025735 | 0.78 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28709934 | 0.78 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31290104 | 0.77 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3999920 | 0.76 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| Trimethylammonium SCHEMBL27993450 | 0.75 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17727833 | 0.75 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7639175 | 0.75 | THRB (0.42) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149375-A1 | IMPROVED ORGANOSILICON COMPOUNDS | RANKA, SEEMA, AJAY (IN) | 2008-12-11 | — | — | WO | claimed |
| US-20080009644-A1 | Organosilicon Compounds | ZYDEX INDUSTRIES | 2008-01-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009644-A1 | Organosilicon Compounds | CUL1, CUL3, MGAM | TSHR 4731/4885THRB 4707/4885POLB 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.