Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | FABP2 | P12104 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10967781 | 0.98 | HPGD (0.53) | HPGDPPARGPPARALMNAMEN1 | |
| Bromomethane SCHEMBL10967617 | 0.97 | HPGD (0.51) | HPGDPPARGPPARALMNAMEN1 | |
| Pivalate SCHEMBL10967155 | 0.93 | PPARA (0.55) | HPGDPPARGPPARALMNAMEN1 | |
| SCHEMBL28619870 | 0.92 | PPARA (0.58) | PPARGPPARAMEN1KMT2AMAPK1 | |
| SCHEMBL21895800 | 0.92 | PPARA (0.58) | PPARGPPARAMEN1KMT2AMAPK1 | |
| SCHEMBL1305299 | 0.92 | PPARA (0.58) | PPARGPPARAMEN1KMT2AMAPK1 | |
| Water SCHEMBL11798405 | 0.91 | PPARA (0.56) | PPARGPPARAMEN1KMT2AMAPK1 | |
| SCHEMBL11536518 | 0.88 | PPARA (0.54) | PPARGPPARAMEN1KMT2ACYP1A2 | |
| SCHEMBL11884564 | 0.88 | ABCB1 (0.62) | HPGDPPARGPPARALMNAMAPK1 | |
| SCHEMBL21992005 | 0.85 | HPGD (0.51) | HPGDPPARGPPARALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135480-A9 | ORAL PHARMACEUTICAL FORMULATIONS COMPRISING FENOFIBRIC ACID AND/OR ITS SALTS | ABBOTT LAB (US) | 2007-02-15 | — | — | WO | claimed |
| EP-0036218-B1 | SALTS OF THE 3-HYDROXY QUINUCLIDINE ESTERS OF A PHENOXYCARBOXYLIC ACID, A PROCESS FOR THE PREPARATION THEREOF, AND RELATED PHARMACEUTICAL COMPOSITIONS | D and D S.r.l. (IT) | 1985-07-31 | — | — | EP | claimed |
| US-4372954-A | LOWERING FIBRINOGEN, ANTICOAGULANTS | MOREAU PIERRE D (FR) | 1983-02-08 | — | — | US | claimed |
| US-4355166-A | Quinuclidinic ester and derivatives of phenoxycarboxylic acids | D AND D S.R.L. (IT) | 1982-10-19 | — | — | US | claimed |
| EP-0036218-A2 | Salts of the 3-hydroxy quinuclidine esters of a phenoxycarboxylic acid, a process for the preparation thereof, and related pharmaceutical compositions | D and D S.r.l. (IT) | 1981-09-23 | — | — | EP | claimed |
| WO-2008157537-A2 | COMPOSITIONS AND METHODS OF USE FOR TREATING OR PREVENTING LIPID RELATED DISORDERS | IRONWOOD PHARMACEUTICALS, INC (US) | 2008-12-24 | — | — | WO | disclosed |
| EP-0256933-B1 | PROCESS FOR PREPARATION OF A MEDICAMENT BASED ON FENOFIBRATE AND MEDICAMENT OBTAINED BY THIS PROCESS | ETHYPHARM (FR) | 1992-05-13 | — | — | EP | disclosed |
| EP-0256933-A1 | Process for preparation of a medicament based on fenofibrate and medicament obtained by this process | ETHYPHARM (FR) | 1988-02-24 | — | — | EP | disclosed |
| EP-0036218-B1 | SALTS OF THE 3-HYDROXY QUINUCLIDINE ESTERS OF A PHENOXYCARBOXYLIC ACID, A PROCESS FOR THE PREPARATION THEREOF, AND RELATED PHARMACEUTICAL COMPOSITIONS | D and D S.r.l. (IT) | 1985-07-31 | — | — | EP | disclosed |
| US-4515809-A | ANTICHOLESTEROL | ALFA FARMACEUTICI S.P.A. (IT) | 1985-05-07 | — | — | US | disclosed |
| US-4378373-A | Derivatives of benzoylphenoxyalkanoic acids having normolipemizing activity | ALFA FARMACEUTICI S.P.A. (IT) | 1983-03-29 | — | — | US | disclosed |
| US-4372954-A | LOWERING FIBRINOGEN, ANTICOAGULANTS | MOREAU PIERRE D (FR) | 1983-02-08 | — | — | US | disclosed |
| EP-0065531-A1 | NEW GALENIC PREPARATION OF PHENOFIBRATE, METHOD FOR THE OBTENTION THEREOF, ITS APPLICATION AS A MEDICINE | DESHORS (FR) | 1982-12-01 | — | — | EP | disclosed |
| US-4355166-A | Quinuclidinic ester and derivatives of phenoxycarboxylic acids | D AND D S.R.L. (IT) | 1982-10-19 | — | — | US | disclosed |
| WO-1982001649-A1 | NEW GALENIC PREPARATION OF PHENOFIBRATE,METHOD FOR THE OBTENTION THEREOF,ITS APPLICATION AS A MEDICINE | LARUELLE CLAUDE | 1982-05-27 | — | — | WO | disclosed |
| US-4296125-A | Derivatives of benzoylphenoxyalkanoic acids having normolipemizing activity | ALPHA FARMACEUTICI S.P.A. (IT) | 1981-10-20 | — | — | US | disclosed |
| EP-0036218-A2 | Salts of the 3-hydroxy quinuclidine esters of a phenoxycarboxylic acid, a process for the preparation thereof, and related pharmaceutical compositions | D and D S.r.l. (IT) | 1981-09-23 | — | — | EP | disclosed |
| US-4233298-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | ORCHIMED SA (CH) | 1980-11-11 | — | — | US | disclosed |
| US-4058552-A | HYPOCHOLESTEROLEMIA, HYPOLIPIDEMIA | ORCHIMED SA (CH) | 1977-11-15 | — | — | US | disclosed |