Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.55 |
| ▸ | PPARG | P37231 | 6/20 | 0.55 |
| ▸ | FABP2 | P12104 | 1/20 | 0.55 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753580 | 0.93 | HPGD (0.54) | PPARAPPARGFABP2SLC22A12ELANE | |
| Hydrochloric Acid SCHEMBL10967781 | 0.92 | HPGD (0.53) | PPARAPPARGFABP2SLC22A12ELANE | |
| Bromomethane SCHEMBL10967617 | 0.91 | HPGD (0.51) | PPARAPPARGFABP2SLC22A12ELANE | |
| SCHEMBL28619870 | 0.86 | PPARA (0.58) | PPARAPPARGMEN1KMT2AMAPK1 | |
| SCHEMBL21895800 | 0.86 | PPARA (0.58) | PPARAPPARGMEN1KMT2AMAPK1 | |
| SCHEMBL1305299 | 0.86 | PPARA (0.58) | PPARAPPARGMEN1KMT2AMAPK1 | |
| Water SCHEMBL11798405 | 0.84 | PPARA (0.56) | PPARAPPARGMEN1KMT2AMAPK1 | |
| Clofibric Acid SCHEMBL147972 | 0.83 | PPARA (0.68) | PPARAPPARGFABP2SLC22A12MEN1 | |
| SCHEMBL11536518 | 0.82 | PPARA (0.54) | PPARAPPARGMEN1KMT2ACYP1A2 | |
| SCHEMBL11884564 | 0.82 | ABCB1 (0.62) | PPARAPPARGELANEHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036218-B1 | SALTS OF THE 3-HYDROXY QUINUCLIDINE ESTERS OF A PHENOXYCARBOXYLIC ACID, A PROCESS FOR THE PREPARATION THEREOF, AND RELATED PHARMACEUTICAL COMPOSITIONS | D and D S.r.l. (IT) | 1985-07-31 | — | — | EP | claimed |
| US-4355166-A | Quinuclidinic ester and derivatives of phenoxycarboxylic acids | D AND D S.R.L. (IT) | 1982-10-19 | — | — | US | claimed |
| EP-0036218-A2 | Salts of the 3-hydroxy quinuclidine esters of a phenoxycarboxylic acid, a process for the preparation thereof, and related pharmaceutical compositions | D and D S.r.l. (IT) | 1981-09-23 | — | — | EP | claimed |
| EP-0036218-B1 | SALTS OF THE 3-HYDROXY QUINUCLIDINE ESTERS OF A PHENOXYCARBOXYLIC ACID, A PROCESS FOR THE PREPARATION THEREOF, AND RELATED PHARMACEUTICAL COMPOSITIONS | D and D S.r.l. (IT) | 1985-07-31 | — | — | EP | disclosed |
| US-4355166-A | Quinuclidinic ester and derivatives of phenoxycarboxylic acids | D AND D S.R.L. (IT) | 1982-10-19 | — | — | US | disclosed |
| EP-0036218-A2 | Salts of the 3-hydroxy quinuclidine esters of a phenoxycarboxylic acid, a process for the preparation thereof, and related pharmaceutical compositions | D and D S.r.l. (IT) | 1981-09-23 | — | — | EP | disclosed |