Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754938 | 0.97 | FFAR1 (0.43) | BRD9FFAR1FFAR4MCHR1MEN1 | |
| SCHEMBL4753246 | 0.93 | HRH3 (0.40) | MCHR1MEN1KMT2ACYP3A4HRH3 | |
| SCHEMBL4753849 | 0.75 | BRD9 (0.47) | BRD9MEN1KMT2AMAPK1KDM4E | |
| SCHEMBL4662895 | 0.74 | MEN1 (0.46) | MEN1KMT2AMAPK1MAPTL3MBTL1 | |
| SCHEMBL13983210 | 0.73 | CYP3A4 (0.48) | BRD9FFAR1FFAR4MEN1KMT2A | |
| SCHEMBL5901519 | 0.73 | KMT2A (0.45) | MEN1KMT2AMAPK1KDM4EALDH1A1 | |
| SCHEMBL5901760 | 0.73 | RHEB (0.49) | FFAR4MEN1KMT2AMAPK1MAPT | |
| SCHEMBL5901935 | 0.73 | HPGD (0.51) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL13097167 | 0.73 | GRM5 (0.54) | FFAR1FFAR4MCHR1CACNA2D1ALDH1A1 | |
| SCHEMBL5901336 | 0.72 | PPIA (0.47) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151927-A2 | 6-N-SUBSTITUTED BENZ IMIDAZOLE DERIVATIVES AS ACID PUMP ANTAGONISTS | NYCOMED GMBH (DE) | 2008-12-18 | — | — | WO | disclosed |