Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755173 | 0.96 | LMNA (0.45) | BRD9LMNAPKMTNIKTP53 | |
| SCHEMBL4755523 | 0.91 | BRD9 (0.36) | BRD9LMNAPKMTNIKSMN1; SMN2 | |
| SCHEMBL4753629 | 0.75 | BRD9 (0.41) | BRD9LMNATP53MAPK1L3MBTL1 | |
| SCHEMBL13983563 | 0.74 | CYP3A4 (0.60) | BRD9LMNAPKMTP53MAPK1 | |
| SCHEMBL13983210 | 0.74 | CYP3A4 (0.48) | BRD9LMNAMAPK1HPGDCYP3A4 | |
| SCHEMBL4754938 | 0.72 | FFAR1 (0.43) | BRD9LMNAMAPK1SMN1; SMN2TSHR | |
| SCHEMBL13983208 | 0.71 | CYP3A4 (0.54) | BRD9LMNAL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL4755121 | 0.71 | CYP3A4 (0.56) | BRD9LMNAPKMTP53MAPK1 | |
| SCHEMBL12996948 | 0.68 | CYP3A4 (0.59) | BRD9LMNAPKMTNIKL3MBTL1 | |
| SCHEMBL4753246 | 0.66 | HRH3 (0.40) | CYP3A4MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151927-A2 | 6-N-SUBSTITUTED BENZ IMIDAZOLE DERIVATIVES AS ACID PUMP ANTAGONISTS | NYCOMED GMBH (DE) | 2008-12-18 | — | — | WO | disclosed |